Please reboot your computer.
Make sure that your windows is uptodate (service packs and windows updates)
Make sure that Microsoft .net framework 3.5 svp 1 is installed
and check that holdemmanager.exe, hmhud.exe and dbcontrolpanel.exe are started as administrator. Run the windows explorer and navigate to your Holdemmanager installation directory. Right click the holdemmanager.exe, dbcontrolpanel.exe and the hmhud.exe executable and select "Run as admin" from the popup menu under compatibilty.